Hi Torsten,
have you tried it without the EDDP scenery? Does the sim crashes also?
What I would try are these steps from our FAQ:
It could be possible that there is any mess in your scenery file which results in this CTD. Also, there are a lot of posting in the MS forum about the BingMaps images which cause also an CTD with addon sceneries (freeware and payware).
Therefore, try the same without the EDDP scenery first.